Antagonism of T-type calcium channels inhibits high-fat diet–induced weight gain in mice

The epidemics of obesity and metabolic disorders have well-recognized health and economic burdens. Pharmacologic treatments for these diseases remain unsatisfactory with respect to both efficacy and side-effect profiles. Here, we have identified a potential central role for T-type calcium channels i...

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Autors principals: Uebele, Victor N., Gotter, Anthony L., Nuss, Cindy E., Kraus, Richard L., Doran, Scott M., Garson, Susan L., Reiss, Duane R., Li, Yuxing, Barrow, James C., Reger, Thomas S., Yang, Zhi-Qiang, Ballard, Jeanine E., Tang, Cuyue, Metzger, Joseph M., Wang, Sheng-Ping, Koblan, Kenneth S., Renger, John J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689113/
https://ncbi.nlm.nih.gov/pubmed/19451696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36954
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