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Phosphorylation-mediated cortical displacement of fate determinants by aPKC during neuroblast asymmetric cell division

BACKGROUND: Asymmetric cell divisions generate daughter cells with distinct fates by polarizing fate determinants into separate cortical domains. Atypical protein kinase C (aPKC) is an evolutionarily conserved regulator of cell polarity. In Drosophila neuroblasts, apically restricted aPKC is require...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Atwood, Scott X., Prehoda, Kenneth E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689075/
https://ncbi.nlm.nih.gov/pubmed/19375318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.03.056
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