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Differential neutralization efficiency of hemagglutinin epitopes, antibody interference, and the design of influenza vaccines
It is generally assumed that amino acid mutations in the surface protein, hemagglutinin (HA), of influenza viruses allow these viruses to circumvent neutralization by antibodies induced during infection. However, empirical data on circulating influenza viruses show that certain amino acid changes to...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2009
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688967/ https://ncbi.nlm.nih.gov/pubmed/19439657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903427106 |
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