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Transcellular biosynthesis of cysteinyl leukotrienes in vivo during mouse peritoneal inflammation
Leukotrienes (LTs) are lipid mediators of inflammation formed by enzymatic oxidation of arachidonic acid. One intriguing aspect of LT production is transcellular biosynthesis: cells expressing 5-lipoxygenase (5LO) form LTA(4) and transfer it to cells expressing LTA(4) hydrolase (LTA(4)H) or LTC(4) s...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688893/ https://ncbi.nlm.nih.gov/pubmed/19416808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903851106 |
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