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Transcellular biosynthesis contributes to the production of leukotrienes during inflammatory responses in vivo
Leukotrienes are lipid mediators that evoke primarily proinflammatory responses by activating receptors present on virtually all cells. The production of leukotrienes is tightly regulated, and expression of 5-lipoxygenase, the enzyme required for the first step in leukotriene synthesis, is generally...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150978/ https://ncbi.nlm.nih.gov/pubmed/12021253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14869 |
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