Transcellular biosynthesis contributes to the production of leukotrienes during inflammatory responses in vivo

Leukotrienes are lipid mediators that evoke primarily proinflammatory responses by activating receptors present on virtually all cells. The production of leukotrienes is tightly regulated, and expression of 5-lipoxygenase, the enzyme required for the first step in leukotriene synthesis, is generally...

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Pubblicato in:	J Clin Invest
Autori principali:	Fabre, Jean-Etienne, Goulet, Jennifer L., Riche, Estelle, Nguyen, MyTrang, Coggins, Kenneth, Offenbacher, Steven, Koller, Beverly H.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 2002
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150978/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12021253/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14869
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