Transcellular biosynthesis contributes to the production of leukotrienes during inflammatory responses in vivo

Leukotrienes are lipid mediators that evoke primarily proinflammatory responses by activating receptors present on virtually all cells. The production of leukotrienes is tightly regulated, and expression of 5-lipoxygenase, the enzyme required for the first step in leukotriene synthesis, is generally...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Fabre, Jean-Etienne, Goulet, Jennifer L., Riche, Estelle, Nguyen, MyTrang, Coggins, Kenneth, Offenbacher, Steven, Koller, Beverly H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2002
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150978/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12021253/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14869
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