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Transcellular biosynthesis of cysteinyl leukotrienes in vivo during mouse peritoneal inflammation

Leukotrienes (LTs) are lipid mediators of inflammation formed by enzymatic oxidation of arachidonic acid. One intriguing aspect of LT production is transcellular biosynthesis: cells expressing 5-lipoxygenase (5LO) form LTA(4) and transfer it to cells expressing LTA(4) hydrolase (LTA(4)H) or LTC(4) s...

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書誌詳細
主要な著者: Zarini, Simona, Gijón, Miguel A., Ransome, Aaron E., Murphy, Robert C., Sala, Angelo
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688893/
https://ncbi.nlm.nih.gov/pubmed/19416808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903851106
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