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Transcellular biosynthesis of cysteinyl leukotrienes in vivo during mouse peritoneal inflammation

Leukotrienes (LTs) are lipid mediators of inflammation formed by enzymatic oxidation of arachidonic acid. One intriguing aspect of LT production is transcellular biosynthesis: cells expressing 5-lipoxygenase (5LO) form LTA(4) and transfer it to cells expressing LTA(4) hydrolase (LTA(4)H) or LTC(4) s...

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Bibliografski detalji
Glavni autori: Zarini, Simona, Gijón, Miguel A., Ransome, Aaron E., Murphy, Robert C., Sala, Angelo
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688893/
https://ncbi.nlm.nih.gov/pubmed/19416808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903851106
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