Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals

Gray matter pathology is increasingly recognized as an important feature of multiple sclerosis (MS), but the nature of the immune response that targets the gray matter is poorly understood. Starting with a proteomics approach, we identified contactin-2/transiently expressed axonal glycoprotein 1 (TA...

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Detalhes bibliográficos
Main Authors: Derfuss, Tobias, Parikh, Khyati, Velhin, Sviataslau, Braun, Magdalena, Mathey, Emily, Krumbholz, Markus, Kümpfel, Tania, Moldenhauer, Anja, Rader, Christoph, Sonderegger, Peter, Pöllmann, Walter, Tiefenthaller, Christian, Bauer, Jan, Lassmann, Hans, Wekerle, Hartmut, Karagogeos, Domna, Hohlfeld, Reinhard, Linington, Christopher, Meinl, Edgar
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688870/
https://ncbi.nlm.nih.gov/pubmed/19416878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901496106
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