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Neurofascin as a novel target for autoantibody-mediated axonal injury

Axonal injury is considered the major cause of disability in patients with multiple sclerosis (MS), but the underlying effector mechanisms are poorly understood. Starting with a proteomics-based approach, we identified neurofascin-specific autoantibodies in patients with MS. These autoantibodies rec...

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Detalhes bibliográficos
Main Authors: Mathey, Emily K., Derfuss, Tobias, Storch, Maria K., Williams, Kieran R., Hales, Kimberly, Woolley, David R., Al-Hayani, Abdulmonem, Davies, Stephen N., Rasband, Matthew N., Olsson, Tomas, Moldenhauer, Anja, Velhin, Sviataslau, Hohlfeld, Reinhard, Meinl, Edgar, Linington, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118456/
https://ncbi.nlm.nih.gov/pubmed/17846150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071053
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