Neurofascin as a target for autoantibodies in peripheral neuropathies

OBJECTIVES: We asked whether autoantibodies against neurofascin (NF)186 or NF155, both localized at the nodes of Ranvier, are present in serum of patients with inflammatory neuropathy, and whether NF-specific monoclonal antibodies are pathogenic in vivo. METHODS: We cloned human NF155 and NF186, and...

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Main Authors: Ng, Judy King Man, Malotka, Joachim, Kawakami, Naoto, Derfuss, Tobias, Khademi, Mohsen, Olsson, Tomas, Linington, Christopher, Odaka, Masaaki, Tackenberg, Björn, Prüss, Harald, Schwab, Jan M., Harms, Lutz, Harms, Hendrik, Sommer, Claudia, Rasband, Matthew N., Eshed-Eisenbach, Yael, Peles, Elior, Hohlfeld, Reinhard, Yuki, Nobuhiro, Dornmair, Klaus, Meinl, Edgar
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542349/
https://ncbi.nlm.nih.gov/pubmed/23100406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e31827689ad
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