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An engineered lipocalin specific for CTLA-4 reveals a combining site with structural and conformational features similar to antibodies
Biomolecular reagents that enable the specific molecular recognition of proteins play a crucial role in basic research as well as medicine. Up to now, antibodies (immunoglobulins) have been widely used for this purpose. Their predominant feature is the vast repertoire of antigen-binding sites that a...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688850/ https://ncbi.nlm.nih.gov/pubmed/19416843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813399106 |
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