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A Tetrahedral Boronic Acid Diester Formed by an Unnatural Amino Acid in the Ligand Pocket of an Engineered Lipocalin

Boronic acids have long been known to form cyclic diesters with cis‐diol compounds, including many carbohydrates. This phenomenon was previously exploited to create an artificial lectin by incorporating p‐borono‐l‐phenylalanine (Bpa) into the ligand pocket of an engineered lipocalin, resulting in a...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Sommer, Carina A., Eichinger, Andreas, Skerra, Arne
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065090/
https://ncbi.nlm.nih.gov/pubmed/31390134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201900405
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