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Blockage of NF-κB by IKKβ- or RelA siRNA Rather Than the NF-κB Super-Suppressor IκBα Mutant Potentiates Adriamycin-induced Cytotoxicity in Lung Cancer Cells
Ambiguous roles of genotoxic anticancer therapeutic-induced NF-κB activation in regulating gene expression (activation or suppression) and apoptosis (anti- or pro-apoptosis) have recently been suggested. In order to clarify this controversy and determine the usefulness of NF-κB blockage for sensitiz...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688738/ https://ncbi.nlm.nih.gov/pubmed/18636537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21856 |
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