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Thrombin Inhibits Nuclear Factor κB and RhoA Pathways in Cytokine-stimulated Vascular Endothelial Cells when EPCR is Occupied by Protein C
The occupancy of endothelial protein C receptor (EPCR) by protein C switches the protease activated receptor 1 (PAR-1)-dependent signaling specificity of thrombin from a permeability enhancing to a barrier protective response in vascular endothelial cells. In this study, the modulatory effects of th...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688729/ https://ncbi.nlm.nih.gov/pubmed/19277413 |
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