Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/β-catenin signaling

Constitutive Hedgehog (Hh) signaling underlies several human tumors1, including basal cell carcinoma (BCC) and basaloid follicular hamartoma in skin2,3. Intriguingly, superficial BCCs arise as de novo epithelial buds resembling embryonic hair germs4–6, collections of epidermal cells whose developmen...

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Main Authors: Yang, Steven Hoseong, Andl, Thomas, Grachtchouk, Vladimir, Wang, Aiqin, Liu, Jianhong, Syu, Li-Jyun, Ferris, Jenny, Wang, Timothy S, Glick, Adam B, Millar, Sarah E, Dlugosz, Andrzej A
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688690/
https://ncbi.nlm.nih.gov/pubmed/19165927
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