Inactivation of Mycobacterium tuberculosis mannosyltransferase pimB reduces the cell wall lipoarabinomannan and lipomannan content and increases the rate of bacterial-induced human macrophage cell death

The Mycobacterium tuberculosis (M.tb) cell wall contains an important group of structurally related mannosylated lipoglycans called phosphatidyl-myo-inositol mannosides (PIMs), lipomannan (LM), and mannose-capped lipoarabinomannan (ManLAM), where the terminal α-[1→2] mannosyl structures on higher or...

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Библиографические подробности
Главные авторы: Torrelles, Jordi B, DesJardin, Lucy E, MacNeil, Jessica, Kaufman, Thomas M, Kutzbach, Beth, Knaup, Rose, McCarthy, Travis R, Gurcha, Sudagar S, Besra, Gurdyal S, Clegg, Steven, Schlesinger, Larry S
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2009
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688391/
https://ncbi.nlm.nih.gov/pubmed/19318518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwp042
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