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Selective amplification of glucocorticoid anti-inflammatory activity through synergistic multi-target action of a combination drug
INTRODUCTION: Glucocorticoids are a mainstay of anti-inflammatory therapy, but significant adverse effects ultimately limit their utility. Previous efforts to design glucocorticoid structures with an increased therapeutic window have focused on dissociating anti-inflammatory transcriptional repressi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688244/ https://ncbi.nlm.nih.gov/pubmed/19171052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2602 |
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