Gene expression profiling in the synovium identifies a predictive signature of absence of response to adalimumab therapy in rheumatoid arthritis

INTRODUCTION: To identify markers and mechanisms of resistance to adalimumab therapy, we studied global gene expression profiles in synovial tissue specimens obtained from severe rheumatoid arthritis (RA) patients before and after initiation of treatment. METHODS: Paired synovial biopsies were obtai...

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Main Authors: Badot, Valérie, Galant, Christine, Nzeusseu Toukap, Adrien, Theate, Ivan, Maudoux, Anne-Lise, Van den Eynde, Benoît J, Durez, Patrick, Houssiau, Frédéric A, Lauwerys, Bernard R
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688209/
https://ncbi.nlm.nih.gov/pubmed/19389237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2678
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