Paired Rheumatoid Arthritis Synovial Biopsies From Small and Large Joints Show Similar Global Transcriptomic Patterns With Enrichment of Private Specificity TCRB and TCR Signaling Pathways

OBJECTIVES: We explored histological and transcriptomic profiles of paired synovial biopsies from rheumatoid arthritis (RA) patients, in order to assess homogeneity in synovial tissue at the individual level. METHODS: Synovial biopsies were performed simultaneously in one small and one large joint p...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Triaille, Clement, Vansteenkiste, Louise, Constant, Manuel, Ambroise, Jérôme, Méric de Bellefon, Laurent, Nzeusseu Toukap, Adrien, Sokolova, Tatiana, Galant, Christine, Coulie, Pierre, Carrasco, Javier, Durez, Patrick, Lauwerys, Bernard R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719799/
https://ncbi.nlm.nih.gov/pubmed/33329580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.593083
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