Influenza B Virus Ribonucleoprotein Is a Potent Activator of the Antiviral Kinase PKR

Activation of the latent kinase PKR is a potent innate defense reaction of vertebrate cells towards viral infections, which is triggered by recognition of viral double-stranded (ds) RNA and results in a translational shutdown. A major gap in our understanding of PKR's antiviral properties conce...

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Main Authors: Dauber, Bianca, Martínez-Sobrido, Luis, Schneider, Jana, Hai, Rong, Waibler, Zoe, Kalinke, Ulrich, García-Sastre, Adolfo, Wolff, Thorsten
格式: Artigo
語言:Inglês
出版: Public Library of Science 2009
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688073/
https://ncbi.nlm.nih.gov/pubmed/19521506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000473
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