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Activation of the Antiviral Kinase PKR and Viral Countermeasures

The interferon-induced double-stranded (ds)RNA-dependent protein kinase (PKR) limits viral replication by an eIF2α-mediated block of translation. Although many negative-strand RNA viruses activate PKR, the responsible RNAs have long remained elusive, as dsRNA, the canonical activator of PKR, has not...

詳細記述

保存先:
書誌詳細
主要な著者: Dauber, Bianca, Wolff, Thorsten
フォーマット: Artigo
言語:Inglês
出版事項: Molecular Diversity Preservation International (MDPI) 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185532/
https://ncbi.nlm.nih.gov/pubmed/21994559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v1030523
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