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Activation of the Antiviral Kinase PKR and Viral Countermeasures

The interferon-induced double-stranded (ds)RNA-dependent protein kinase (PKR) limits viral replication by an eIF2α-mediated block of translation. Although many negative-strand RNA viruses activate PKR, the responsible RNAs have long remained elusive, as dsRNA, the canonical activator of PKR, has not...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dauber, Bianca, Wolff, Thorsten
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Molecular Diversity Preservation International (MDPI) 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185532/
https://ncbi.nlm.nih.gov/pubmed/21994559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v1030523
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