STAT1 Pathway Mediates Amplification of Metastatic Potential and Resistance to Therapy

BACKGROUND: Traditionally IFN/STAT1 signaling is connected with an anti-viral response and pro-apoptotic tumor-suppressor functions. Emerging functions of a constitutively activated IFN/STAT1 pathway suggest an association with an aggressive tumor phenotype. We hypothesized that tumor clones that co...

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Detaylı Bibliyografya
Asıl Yazarlar: Khodarev, Nikolai N., Roach, Paul, Pitroda, Sean P., Golden, Daniel W., Bhayani, Mihir, Shao, Michael Y., Darga, Thomas E., Beveridge, Mara G., Sood, Ravi F., Sutton, Harold G., Beckett, Michael A., Mauceri, Helena J., Posner, Mitchell C., Weichselbaum, Ralph R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2009
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688034/
https://ncbi.nlm.nih.gov/pubmed/19503789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005821
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