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20-Hydroxylation is the CYP-dependent and retinoid-inducible leukotriene B4 inactivation pathway in human and mouse skin cells

Metabolic inactivation of leukotriene B4 (LTB4) is an innate mechanism to resolve tissue inflammation. We studied the nine Cyp4f genes in the mouse genome, measuring cutaneous transcript levels by real-time polymerase chain reaction, and LTB4 metabolism in mouse and human skin. Transcripts arising f...

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Detalhes bibliográficos
Main Authors: Du, Liping, Yin, Huiyong, Morrow, Jason D., Strobel, Henry W., Keeney, Diane S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687325/
https://ncbi.nlm.nih.gov/pubmed/19467632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.01.012
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