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Inhibition of Vaccinia Virus Replication by Two Small Interfering RNAs Targeting B1R and G7L Genes and Their Synergistic Combination with Cidofovir

In view of the threat of the potential use of variola virus in a terrorist attack, considerable efforts have been performed to develop new antiviral strategies against orthopoxviruses. Here we report on the use of RNA interference, either alone or in combination with cidofovir, as an approach to inh...

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Bibliografiske detaljer
Main Authors: Vigne, Solenne, Duraffour, Sophie, Andrei, Graciela, Snoeck, Robert, Garin, Daniel, Crance, Jean-Marc
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687203/
https://ncbi.nlm.nih.gov/pubmed/19307376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01626-08
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