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Inhibition of Vaccinia Virus Replication by Two Small Interfering RNAs Targeting B1R and G7L Genes and Their Synergistic Combination with Cidofovir

In view of the threat of the potential use of variola virus in a terrorist attack, considerable efforts have been performed to develop new antiviral strategies against orthopoxviruses. Here we report on the use of RNA interference, either alone or in combination with cidofovir, as an approach to inh...

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Autors principals: Vigne, Solenne, Duraffour, Sophie, Andrei, Graciela, Snoeck, Robert, Garin, Daniel, Crance, Jean-Marc
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687203/
https://ncbi.nlm.nih.gov/pubmed/19307376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01626-08
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