Losartan, an angiotensin-II type 1 receptor blocker, attenuates the liver fibrosis development of non-alcoholic steatohepatitis in the rat

BACKGROUND: Apart from simple steatosis, the non-alcoholic steatohepatitis (NASH) can progress into liver fibrosis and cirrhosis. To date, however, no widely accepted therapeutic modalities have been established against NASH in the clinical practice. To find out promising new therapeutic agents, it...

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Hlavní autoři: Yoshiji, Hitoshi, Noguchi, Ryuichi, Ikenaka, Yasuhide, Namisaki, Tadashi, Kitade, Mitsuteru, Kaji, Kosuke, Shirai, Yusaku, Yoshii, Junichi, Yanase, Koji, Yamazaki, Masaharu, Tsujimoto, Tatsuhiro, Kawaratani, Hideto, Akahane, Takemi, Aihara, Yosuke, Fukui, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
Short Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686718/
https://ncbi.nlm.nih.gov/pubmed/19416517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-2-70
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