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Losartan, an angiotensin-II type 1 receptor blocker, attenuates the liver fibrosis development of non-alcoholic steatohepatitis in the rat

BACKGROUND: Apart from simple steatosis, the non-alcoholic steatohepatitis (NASH) can progress into liver fibrosis and cirrhosis. To date, however, no widely accepted therapeutic modalities have been established against NASH in the clinical practice. To find out promising new therapeutic agents, it...

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Detalhes bibliográficos
Main Authors: Yoshiji, Hitoshi, Noguchi, Ryuichi, Ikenaka, Yasuhide, Namisaki, Tadashi, Kitade, Mitsuteru, Kaji, Kosuke, Shirai, Yusaku, Yoshii, Junichi, Yanase, Koji, Yamazaki, Masaharu, Tsujimoto, Tatsuhiro, Kawaratani, Hideto, Akahane, Takemi, Aihara, Yosuke, Fukui, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686718/
https://ncbi.nlm.nih.gov/pubmed/19416517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-2-70
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