A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages

BACKGROUND: Macrophages and dendritic cells (DCs) play key roles in host defense against HSV-1 infection. Although macrophages and DCs can be infected by herpes simplex virus type 1 (HSV-1), both cell types are resistant to HSV-1 replication. The aim of our study was to determine factor (s) that are...

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Autors principals: Mott, Kevin R, UnderHill, David, Wechsler, Steven L, Town, Terrence, Ghiasi, Homayon
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686698/
https://ncbi.nlm.nih.gov/pubmed/19439086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-6-56
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