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CCR2(+) migratory macrophages with M1 status are the early-responders in the cornea of HSV-1 infected mice

Complex interactions between HSV-1 and infiltrating immune cells play important roles in establishing localized, acute virus replication as well as chronic latent infection. The extent and duration of initial virus replication are the key determinants of subsequent pathologic inflammatory responses...

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Pubblicato in:PLoS One
Autori principali: Lee, Dhong Hyun, Jaggi, Ujjaldeep, Ghiasi, Homayon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472814/
https://ncbi.nlm.nih.gov/pubmed/30998796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215727
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