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Differential Role of Autophagy in CD4 T Cells and Macrophages during X4 and R5 HIV-1 Infection
BACKGROUND: HIV-1 can infect and replicate in both CD4 T cells and macrophages. In these cell types, HIV-1 entry is mediated by the binding of envelope glycoproteins (gp120 and gp41, Env) to the receptor CD4 and a coreceptor, principally CCR5 or CXCR4, depending on the viral strain (R5 or X4, respec...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2686268/ https://ncbi.nlm.nih.gov/pubmed/19492063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005787 |
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