Differential Role of Autophagy in CD4 T Cells and Macrophages during X4 and R5 HIV-1 Infection

BACKGROUND: HIV-1 can infect and replicate in both CD4 T cells and macrophages. In these cell types, HIV-1 entry is mediated by the binding of envelope glycoproteins (gp120 and gp41, Env) to the receptor CD4 and a coreceptor, principally CCR5 or CXCR4, depending on the viral strain (R5 or X4, respec...

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Main Authors: Espert, Lucile, Varbanov, Mihayl, Robert-Hebmann, Véronique, Sagnier, Sophie, Robbins, Ian, Sanchez, Françoise, Lafont, Virginie, Biard-Piechaczyk, Martine
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686268/
https://ncbi.nlm.nih.gov/pubmed/19492063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005787
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