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Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4
HIV-1 envelope glycoproteins (Env), expressed at the cell surface, induce apoptosis of uninfected CD4(+) T cells, contributing to the development of AIDS. Here we demonstrate that, independently of HIV replication, transfected or HIV-infected cells that express Env induced autophagy and accumulation...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1523410/ https://ncbi.nlm.nih.gov/pubmed/16886061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26185 |
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