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Conditional deletion of STAT5 in adult mouse hematopoietic stem cells causes loss of quiescence and permits efficient nonablative stem cell replacement

Currently, there is a major need in hematopoietic stem cell (HSC) transplantation to develop reduced-intensity regimens that do not cause DNA damage and associated toxicities and that allow a wider range of patients to receive therapy. Cytokine receptor signals through c-Kit and c-Mpl can modulate H...

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Bibliografski detalji
Glavni autori: Wang, Zhengqi, Li, Geqiang, Tse, William, Bunting, Kevin D.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686137/
https://ncbi.nlm.nih.gov/pubmed/19258595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-09-181107
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