Airway Epithelial Inflammation-induced Endoplasmic Reticulum Ca(2+) Store Expansion Is Mediated by X-box Binding Protein-1

Inflamed cystic fibrosis (CF) human bronchial epithelia (HBE), or normal HBE exposed to supernatant from mucopurulent material (SMM) from CF airways, exhibit endoplasmic reticulum (ER)/Ca(2+) store expansion and amplified Ca(2+)-mediated inflammation. HBE inflammation triggers an unfolded protein re...

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Autors principals: Martino, Mary E. B., Olsen, John C., Fulcher, Nanette B., Wolfgang, Matthew C., O'Neal, Wanda K., Ribeiro, Carla M. P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Mechanisms of Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685672/
https://ncbi.nlm.nih.gov/pubmed/19321437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809180200
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