Transmembrane Protein 16A (TMEM16A) Is a Ca(2+)-regulated Cl(–) Secretory Channel in Mouse Airways

For almost two decades, it has been postulated that calcium-activated Cl(–) channels (CaCCs) play a role in airway epithelial Cl(–) secretion, but until recently, the molecular identity of the airway CaCC(s) was unknown. Recent studies have unequivocally identified TMEM16A as a glandular epithelial...

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Detalhes bibliográficos
Main Authors: Rock, Jason R., O'Neal, Wanda K., Gabriel, Sherif E., Randell, Scott H., Harfe, Brian D., Boucher, Richard C., Grubb, Barbara R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Membrane Transport, Structure, Function, and Biogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685669/
https://ncbi.nlm.nih.gov/pubmed/19363029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.000869
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