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Crystal Structure of the GTPase-activating Protein-related Domain from IQGAP1
IQGAP1 is a 190-kDa molecular scaffold containing several domains required for interaction with numerous proteins. One domain is homologous to Ras GTPase-activating protein (GAP) domains. However, instead of accelerating hydrolysis of bound GTP on Ras IQGAP1, using its GAP-related domain (GRD) binds...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685667/ https://ncbi.nlm.nih.gov/pubmed/19321438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808974200 |
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