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New experimental approaches for investigating interactions between Pyrococcus furiosus carbamate kinase and carbamoyltransferases, enzymes involved in the channeling of thermolabile carbamoyl phosphate

A somewhat neglected but essential aspect of the molecular physiology of hyperthermophiles is the protection of thermolabile metabolites and coenzymes. An example is carbamoyl phosphate (CP), a precursor of pyrimidines and arginine, which is an extremely labile and potentially toxic intermediate. Th...

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Библиографические подробности
Главные авторы: Massant, Jan, Glansdorff, Nicolas
Формат: Artigo
Язык:Inglês
Опубликовано: Heron Publishing 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685582/
https://ncbi.nlm.nih.gov/pubmed/16243776
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