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Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy
BACKGROUND: The COP9/signalosome (CSN) is a highly conserved eight subunit complex that, by deneddylating cullins in cullin-based E3 ubiquitin ligases, regulates protein degradation. Although studied in model human cell lines such as HeLa, very little is known about the role of the CSN in haemopoiet...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685372/ https://ncbi.nlm.nih.gov/pubmed/19400951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-10-31 |
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