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NMR Analysis of the Closed Conformation of Syntaxin-1
The Sec1/Munc18 (SM) protein Munc18-1 and the SNAREs syntaxin-1, SNAP-25 and synaptobrevin form the core of the membrane fusion machinery that triggers neurotransmitter release. Munc18-1 binds to syntaxin-1 folded into a closed conformation and to the SNARE complex formed by the three SNAREs, which...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685195/ https://ncbi.nlm.nih.gov/pubmed/18458823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-008-9239-1 |
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