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Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells
Small RNAs targeted to gene promoters in human cells can mediate transcriptional gene silencing (TGS) by directing silent state epigenetic modifications to targeted loci. Many mechanistic details of this process remain poorly defined, and the ability to stably modulate gene expression in this manner...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685082/ https://ncbi.nlm.nih.gov/pubmed/19304753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp127 |
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