Llwytho...

Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells

Small RNAs targeted to gene promoters in human cells can mediate transcriptional gene silencing (TGS) by directing silent state epigenetic modifications to targeted loci. Many mechanistic details of this process remain poorly defined, and the ability to stably modulate gene expression in this manner...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hawkins, Peter G., Santoso, Sharon, Adams, Christopher, Anest, Vasiliki, Morris, Kevin V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685082/
https://ncbi.nlm.nih.gov/pubmed/19304753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp127
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