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The Mamu B*17-restricted SIV Nef IW9 to TW9 mutation abrogates correct epitope processing and presentation without loss of replicative fitness
CD8(+) cytotoxic T lymphocytes (CTL) play an important role in controlling virus replication in HIV- and SIV-infected humans and monkeys, respectively. Three well-studied SIV CTL determinants are the two Mamu A*01-restricted epitopes Gag CM9 and Tat SL8, and the Mamu B*17-restricted epitope Nef IW9....
Tallennettuna:
| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2684690/ https://ncbi.nlm.nih.gov/pubmed/18328525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.02.005 |
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