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Dose Escalation Methods in Phase I Cancer Clinical Trials
Phase I clinical trials are an essential step in the development of anticancer drugs. The main goal of these studies is to establish the recommended dose and/or schedule of new drugs or drug combinations for phase II trials. The guiding principle for dose escalation in phase I trials is to avoid exp...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2684552/ https://ncbi.nlm.nih.gov/pubmed/19436029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djp079 |
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