Divergent Frequencies of IGF-I Receptor-Expressing Blood Lymphocytes in Monozygotic Twin Pairs Discordant for Graves’ Disease: Evidence for a Phenotypic Signature Ascribable to Nongenetic Factors

Context: Graves’ disease (GD) is an autoimmune process of the thyroid and orbital connective tissues. The fraction of T and B cells expressing IGF-I receptor (IGF-IR) is increased in GD. It is a potentially important autoantigen in GD. Susceptibility to GD arises from both genetic and acquired facto...

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Main Authors: Douglas, Raymond S., Brix, Thomas H., Hwang, Catherine J., Hegedüs, Laszlo, Smith, Terry J.
Formato: Artigo
Idioma:Inglês
Publicado: The Endocrine Society 2009
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684473/
https://ncbi.nlm.nih.gov/pubmed/19240157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-2810
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