Atherosclerosis in LDLR-Knockout Mice Is Inhibited, but Not Reversed, by the PPARγ Ligand Pioglitazone

Thiazolidinediones, a class of drugs for the treatment of type-2 diabetes, are synthetic ligands for peroxisome proliferator-activated receptor-γ. They have been demonstrated to possess cardioprotective effects in humans and anti-atherogenic properties in animal models. However, the question remains...

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Detalhes bibliográficos
Main Authors: Nakaya, Hideaki, Summers, Barbara D., Nicholson, Andrew C., Gotto, Antonio M., Hajjar, David P., Han, Jihong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Short Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684166/
https://ncbi.nlm.nih.gov/pubmed/19435790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080611
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