Disposition of Flavonoids via Enteric Recycling: UDP-Glucuronosyltransferase (UGT) 1As Deficiency in Gunn Rats Is Compensated by Increases in UGT2Bs Activities

Flavonoids have poor bioavailabilities largely because of metabolism via UDP-glucuronosyltransferases (UGTs). This study aims to further understand the functions of UGT in metabolizing genistein and apigenin, two compounds metabolized more extensively in the gut than in the liver. Because Gunn rats...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Wang, Stephen W. J., Kulkarni, Kaustubh H., Tang, Lan, Wang, Jing Rong, Yin, Taijun, Daidoji, Tomo, Yokota, Hiroshi, Hu, Ming
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Pharmacology and Experimental Therapeutics 2009
विषय:
Metabolism, Transport, and Pharmacogenomics
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683779/
https://ncbi.nlm.nih.gov/pubmed/19264971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.147371
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