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Mimicking Ndc80 phosphorylation triggers spindle assembly checkpoint signalling
The protein kinase Mps1 is, among others, essential for the spindle assembly checkpoint (SAC). We found that Saccharomyces cerevisiae Mps1 interacts physically with the N-terminal domain of Ndc80 (Ndc80(1−257)), a constituent of the Ndc80 kinetochore complex. Furthermore, Mps1 effectively phosphoryl...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2683709/ https://ncbi.nlm.nih.gov/pubmed/19300438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.62 |
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