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Coordination of dual incision and repair synthesis in human nucleotide excision repair

Nucleotide excision repair (NER) requires the coordinated sequential assembly and actions of the involved proteins at sites of DNA damage. Following damage recognition, dual incision 5′ to the lesion by ERCC1-XPF and 3′ to the lesion by XPG leads to the removal of a lesion-containing oligonucleotide...

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Detalhes bibliográficos
Main Authors: Staresincic, Lidija, Fagbemi, Adebanke F, Enzlin, Jacqueline H, Gourdin, Audrey M, Wijgers, Nils, Dunand-Sauthier, Isabelle, Giglia-Mari, Giuseppina, Clarkson, Stuart G, Vermeulen, Wim, Schärer, Orlando D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683701/
https://ncbi.nlm.nih.gov/pubmed/19279666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.49
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